How does Viagra work molecular?
Physically, Viagra works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which normally cleaves cyclic guanosine monophosphate (cGMP), a compound that promotes smooth-muscle relaxation in the corpus cavernosum, thus enhancing blood flow.
What molecule does Viagra inhibit?
Sildenafil (Viagra), a specific PDE5 inhibitor, promotes penile erection by blocking the activity of PDE5, which causes cGMP to accumulate in the corpus cavernosum.
What is the chemical structure of Viagra?
Sildenafil is a pyrazolo[4,3-d]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position. It has a role as a vasodilator agent and an EC 3.1. 4.35 (3′,5′-cyclic-GMP phosphodiesterase) inhibitor.
What are the side effects of Viagra?
The most common side effects are headaches, feeling sick, hot flushes and dizziness. Many men have no side effects or only mild ones. It can be dangerous to take sildenafil if you also take medicines called nitrates (often given for chest pain). The combination can cause a dangerous fall in your blood pressure.
What is the chemical name for Cialis?
The chemical designation is pyrazino[1′;,2′;:1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-. It is a crystalline solid that is practically insoluble in water and very slightly soluble in ethanol.
What was sildenafil originally used for?
Sildenafil, the chemical name for Viagra, is an artificial compound that was originally synthesized and studied to treat hypertension (high blood pressure) and angina pectoris (a form of cardiovascular disease).
What enzyme does Viagra suppress?
Viagra works by inhibiting one specific type of enzyme called a cyclic GMP phosphodiesterase. “There is not just one, but many phosphodiesterases.
What is the molecular weight of Viagra?
474.6 g/mol
Sildénafil/Masse molaire
