Où agissent les corticoïdes ?
Les mécanismes par lesquels les corticoïdes agissent sont multiples et complexes. Schématiquement, après leur absorption, les corticoïdes agissent sur les cellules de tout l’organisme par le biais d’un récepteur spécifique à la surface de la membrane des cellules.
Quelles sont les corticoïdes ?
Les corticoïdes ou anti-inflammatoires stéroïdiens (cortisone, prednisone, methylprednisolone…) sont utilisés pour soulager des inflammations aiguës, liées notamment à des affections pulmonaires, rhumatologiques, digestives ou allergiques.
What is the mechanism of action of corticosteroids?
- The major action of corticosteroids is to switch off multiple activated inflammatory genes that encode for cytokines, chemokines, adhesion molecules inflammatory enzymes and receptors [1].
What are the effects of corticosteroids on mental health?
- Reported psychiatric disturbances include depression, euphoria, insomnia, mood swings, and personality changes. Psychotic behaviors also have been reported. Corticosteroids, since they suppress the immune system, can lead to an increase in the rate of infections and reduce the effectiveness of vaccines and antibiotics.
What are inhaled corticosteroids?
- Inhaled corticosteroids (ICS, also known as glucocorticosteroids, glucocorticoids, steroids) are by far the most effective controllers used in the treatment of asthma and the only drugs that can effectively suppress the characteristic inflammation in asthmatic airways, even in very low doses.
What are glucocorticoid corticosteroids used for?
- allergic or inflammatory conditions involving the nose and eyes. Glucocorticoid corticosteroids are used to treat systemic lupus, severe psoriasis, leukemia, lymphomas, idiopathic thrombocytopenic purpura, and autoimmune hemolytic anemia.
